Welcome to the Molecular Therapeutic Approaches to Genetic Diseases and Cancer team website. We are located at the ONCOLille Institute within the Canther unit on the Lille University Hospital campus. We study the mechanisms of recognition of premature termination codons and develop therapeutic approaches aimed at correcting or exploiting premature termination codons in genetic diseases and cancer. Indeed, nonsense mutations that transform a codon into a premature termination of protein translation are the cause of 10% of cases of genetic diseases such as cystic fibrosis, Duchenne muscular dystrophy or hemophilia, and many forms of cancer. We are therefore at the interface between fundamental research and applied research. If you would like to learn more about rare genetic diseases and the development of therapies, here is the link to the first episode of a series of videos which will answer many questions and which is intended for all audiences.

https://www.youtube.com/watch?v=lCXdySASE1Y